Ruane Miller studied at The College of Fine and Applied Arts, Rochester Institute of Technology in Rochester, New York for a MFA degree in Computer Graphics Design and at the Tyler School of Art of Temple University in Rome, Italy for a MFA degree in Painting and Printmaking and in Philadelphia for her undergraduate BFA degree.

She has exhibited her work extensively in national and international solo, group, and juried exhibits. Her work is in numerous public and private national and international collections and has been recognized through numerous awards, grants, and fellowships. She is a recipient of Residency Fellowships at the Ucross Foundation in Wyoming and from the National Park Service at the North Rim Grand Canyon and at the Petrified Forest National Park in Arizona.

Ruane is a Professor of Art at The College of New Jersey where she has taught since 1986. She has served as Chairperson of the Art Department, Coordinator of Fine Arts and of Digital Arts. She developed and implemented the computer graphics/digital arts curriculum and facilities for the Art Department. She has taught on the college level since 1977 in other teaching positions at UCLA, SUNY Albany, and Lycoming College in the areas of Digital Media, Painting, Silk Screen Printmaking, Drawing, Design, and Art History.