Ruane Miller studied at The College of Fine and Applied Arts, Rochester Institute of Technology in Rochester, New York for a MFA degree in Computer Graphics Design and at the Tyler School of Art of Temple University in Rome, Italy for a MFA degree in Painting and Printmaking and in Philadelphia for her undergraduate BFA degree.

She has exhibited her work extensively in national and international solo, group, and juried exhibits. Her work is in numerous public and private national and international collections including the Print Collection of the Philadelphia Museum of Art; Museum of Art; Print Collection, San Francisco; Mercer County, New Jersey, Cultural Commission Permanent Collection. Her work has been recognized through numerous awards, grants, and fellowships. She was a recipient of a Residency Fellowship at the Ucross Foundation in Wyoming and has been awarded numerous Faculty Research Awards from The College of New Jersey.

Ruane is a Professor of Art at The College of New Jersey where she has taught since 1986. She has served as Chairperson of the Art Department, Coordinator of Fine Arts and of Digital Arts. She developed and implemented the computer graphics curriculum and facilities for the Art Department and is currently coordinating the development of a new BFA major in Digital Arts. She has taught on the college level since 1977 in other teaching positions at UCLA, SUNY Albany, and Lycoming College in the areas of Digital Media, Painting, Silk Screen Printmaking, Drawing, Design, and Art History.